CARRASCO YÉPEZ MARÍA MARICELA
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Contact:
Email: cayem07@yahoo.com.mx
Information.
my current area of interest has been focused in the characterization of some factors associated to the immune response and the protein interactions of Naegleria fowleri with the host cells in experimental model of mice. We are searching specific antigenic determinants (by molecular, proteomic or bioinformatics tools) responsible for the pathogenicity and immunogenicity of N. fowleri with the aim of proposing therapeutic targets for the design of vaccines against the meningoencephalitis due to N. fowleri.
Links of Interest.
1) Gutiérrez-Sánchez M, Carrasco-Yépez MM, Correa-Basurto J, Ramírez-Salinas GL, Rojas-Hernández S. Two MP2CL5 Antigen Vaccines from Naegleria fowleri Stimulate the Immune Response against Meningitis in the BALB/c Model. Infect Immun. 2023 Jul 18;91(7):e0018123. doi: 10.1128/iai.00181-23. Epub 2023 Jun 5. PMID: 37272791; PMCID: PMC10353451.
2) Rojas-Ortega DA, Rojas-Hernández S, Sánchez-Mendoza ME, Gómez-López M, Sánchez-Camacho JV, Rosales-Cruz E, Yépez MMC. Role of FcγRIII in the nasal cavity of BALB/c mice in the primary amebic meningoencephalitis protection model. Parasitol Res. 2023 May;122(5):1087-1105. doi: 10.1007/s00436-023-07810-w. Epub 2023 Mar 13. PMID: 36913025; PMCID: PMC10009362.
3) Role of cathepsin B of Naegleria fowleri during primary amebic meningoencephalitis. Rodríguez- Mera IB, Carrasco-Yépez MM, Vásquez-Moctezuma I, Correa-Basurto J, Salinas GR, Castillo-Ramírez DA, Rosales-Cruz É, Rojas-Hernández S. Parasitol Res. 2022 Nov;121(11):3287-3303. doi: 10.1007s00436-022-07660-y. Epub 2022 Sep 20. PMID: 36125528.
4) A 250-kDa glycoprotein of Naegleria fowleri induces protection and modifies the expression of α4β1 and LFA-1 on T and B lymphocytes in mouse meningitis model. Castillo-Ramírez DA, Carrasco- Yépez MM, Rodríguez-Mera IB, Reséndiz-Albor AA, Rosales-Cruz É, Rojas-Hernández S. Parasite Immunol. 2021 Dec;43(12):e12882. doi: 10.1111pim.12882. Epub 2021 Oct 11. PMID: 34570374.
5) Identification of differential protein recognition pattern between Naegleria fowleri and Naegleria lovaniensis. Gutiérrez-Sánchez M, Carrasco-Yepez MM, Herrera-Díaz J, Rojas-Hernández S. Parasite Immunol. 2020 Jun;42(6):e12715. doi: 10.1111pim.12715. Epub 2020 Apr 28. PMID: 32191816.