
Location within campus: | CUSI Almaraz on Odontological Research Laboratory and Aragon Clinic |
Phone: | 55 5870 5701 and 5527547471 |
Head of Laboratory: | Dr. Alejandro García Muñoz Full Professor alexandro_06@hotmail.com |
Researchers affiliated to the laboratory: | Clínica odontológica Aragon: 1. Gómez Hernández Pabel Antonio (oral pathologist) paangohe@hotmail.com 2. Claudia Araceli Torres Urbina. (Maxillofacial Surgeon) dratorresurbina@hotmail.com 3. Cynthia Georgina Trejo Irarte (Sc. D.) cynthia.belegii@gmail.com 4. Jose Ramírez Vega (Surgeon) 5. Marisa Canela Riveron (Dental Surgeon) 6. Esp. Jesús Nápoles Martínez (Endodontics) 7. Mtra. Martha L. Flores Sánchez marthal_flores@hotmail.com 8. Felipe Vaca Paniagua (Sc. D. ) felipe.vaca@gmail.com 9. Ronaldo González López (Orthodontics) nterortsat@hotmail.com 10. Ibarra González Felipe De Jesús (Maxillofacial Surgeon) f_ibarra77@hotmail.com 11. Roberto Benítez Hernández (Maxillofacial Surgeon) 12. Jesús Juárez Manrique (Maxillofacial Prosthodontist) |
Research lines per researcher: | Search for therapeutic targets in odontogenic tumors and cysts. Identification of biomarkers in odontogenic tumors and autoimmune diseases. Analysis of potential therapeutic targets in odontogenic tumors. Saliva analysis in patients with odontogenic tumors and oral pathologies. Results analysis, clinical approach, clinical diagnosis and research. |

The research lines are focused on determining tumor biomarkers, identifying therapeutic targets, and associating the biological behavior with the molecular profile expressed by each of the analyzed lesions such as tumors, cysts, and oral pathologies. Additionally, this laboratory collaborates with other institutions to obtain fresh samples for genomic Next-Generation Sequencing, proteomics, flow cytometry, cell cultures, nanoparticles, histology, and histopathological analysis.All of the above aims to early detect pathologies that require invasive treatments, as well as identify genes that may negatively regulate the growth of tumor cells or induce apoptosis or cell death. Lastly, it involves mass detection of gene and protein expression that may govern the biological behavior of tumors, cysts, and oral pathologies.

1. 2018 Analysis of proteinic profile in oral lichen planus. Flores-Luna María Guadalupe1, López-Ávila Beatriz Elizabeth1, Liceaga-Escalera Carlos, Trejo-Iriarte Cynthia Georgina, Mario A Rodríguez, Gómez-Clavel José Francisco, Hernández-López Hegel Rafael, Hegel Rafael and García-Muñoz Alejandro. Integr Mol Med. Volume 5(1): 1-7. 2018.
2. 2016 Orosomucoid-1 Expression in Ameloblastoma Variants. Alejandro García-Muñoz, Ronell Bologna-Molina, Mario A. Rodríguez, Rodrigo Liceaga-Reyes, Jose Eduardo Farfán-Morales, Saray Aranda-Romo, Nelly Molina-Frechero, Rogelio Gonzalez-Gonzalez. Int J Mol Cell Med, Winter 2016; Vol 5 No 1
3. 2019. Gómez Clavel JF, Vences DT, Valdiviezo AC, Peña Castillo E, García Muñoz A, Trejo Iriarte CG. Correlation between caries history and laser fluorescence of sound tooth enamel in restored and unrestored dentition. J Oral Sci. 2019 Aug 28;61(3):441-446. Doi 10.2334/josnusd.18-0183. Epub 2019 Jul 26.
4. 2015 Expression of the transcription factor PITX2 in ameloblastic carcinoma. García-Muñoz A, Rodríguez MA, Licéaga-Escalera C, Licéaga-Reyes R, Carreón-Burciaga RG, González-González R, Bologna-Molina R. Arch Oral Biol. 2015 Feb 28;60(6):799-803.
5. 2014 Identification of proteins with increased levels in ameloblastic carcinoma. García-Muñoz A, Bologna-Molina R, Aldape-Barrios B, Licéaga-Escalera C,Montoya-Pérez LA, Rodríguez MA. J Oral Maxillofac Surg. 2014 Jun;72(6):1183-96.

Prospective Thesis Candidate Profile: | English language reading comprehension, with an average score of 8 or higher, and a strong desire to learn. |
Service Social Data: | Collection of samples in hospitals or clinics, experimentation, results analysis, writing and reviewing articles, assisting in patient reviews, and recording epidemiological data at the Aragon Clinic, detection of potentially invasive or challenging to diagnose pathologies. |