Molecular Biology of Eukaryotic Microorganisms

Location within campus: Biomedical Research Unit
Phone:56231333 ext. 39772
Head of Laboratory: Dr. Claudia Marissa Calderón Torres
Associate Professor, Full time, Tenured.
cmarissacalderon@gmail.com
Research lines per researcher: Study of the transcriptional regulation of yeast during salt and oxidative stress for its biotechnological application in biomedicine. Research Group DEHA, http://www.deha.abaco2.org/

The study of transcription regulation in extremophilic yeasts of biotechnological and commercial interest allows determining the regulation of gene expression in response to salt and oxidative stress. Once stress-responsive genes are identified, their biotechnological application in medicine is pursued.

Calderón-Torres, C. M., Sarabia-Cruz, L., Ledesma-Soto, Y., Murguía-Romero, M. & Terrazas, L. I. (2019). Denitrase activity of Debaryomyces hansenii reduces the oxidized compound 3-nitrotyrosine in mice liver with colitis. Experimental and Therapeutic Medicine, 17, 3748-3754.

Calderón-Torres, M., López-Estrada, E., Romero-Maldonado, A., Rosales-Mendoza, S. & Murguía-Romero, M. (2019). The heterologous expression of the Debaryomyces hansenii DhARO4 gene in Nicotiana tabacum improves growth yield, even after inhibition by saline stress. Revista Mexicana de Ingeniería Química, 18 (2), 729-736.

Castro, D. E., Murguía-Romero M., Thomé P.E., Peña A. & Calderón-Torres, M. (2017). Putative 3-nitrotyrosine detoxifying genes identified in the yeast Debaryomyces hansenii: In silico search of regulatory sequences responsive to salt and nitrogen stress. Electronic Journal of Biotechnology, 29, 1–6.

Ortíz-Reyes, A. E. & Calderón-Torres, C. M. (2017). Incremento de la expresión de TLR4 y efecto antioxidante del ácido acetilsalicílico en conejos con dieta alta en grasas. Revista de Salud Pública y Nutrición, 16( 2), 1-10.

Potential Thesis Candidates’ Admission Profile:The service development is designed for students in the Bachelor’s programs in Biology and Pharmaceutical Chemistry-Biology, who have basic knowledge of Chemistry, Biomolecules, and Genetics.
Social Service Data:Intern from the Bachelor’s program in Biology at FES Iztacala: Claudia Adriana González Romero Enrolled in the Social Service Program: Applications of Extremophilic Yeast Biotechnology “Debaryomyces hansenii” Using the program key: 2020-12/63-2656